Triple

T16803397
Position Surface form Disambiguated ID Type / Status
Subject Trost asymmetric allylic alkylation E408414 entity
Predicate belongsToClass P1244 FINISHED
Object Tsuji–Trost reactions
Tsuji–Trost reactions are palladium-catalyzed allylic substitution processes widely used in organic synthesis to form carbon–carbon and carbon–heteroatom bonds with high regio- and stereocontrol.
E1233134 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Tsuji–Trost reactions | Statement: [Trost asymmetric allylic alkylation, belongsToClass, Tsuji–Trost reactions]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Tsuji–Trost reactions
Context triple: [Trost asymmetric allylic alkylation, belongsToClass, Tsuji–Trost reactions]
  • A. Eschenmoser sulfide contraction
    Eschenmoser sulfide contraction is an organic rearrangement reaction that converts certain sulfur-containing intermediates into carbonyl compounds, widely used in complex molecule and natural product synthesis.
  • B. Stork enamine reaction
    The Stork enamine reaction is a key carbon–carbon bond-forming method in organic chemistry that uses enamines as nucleophiles to alkylate or acylate carbonyl compounds in a controlled, selective way.
  • C. Buchwald–Hartwig amination
    The Buchwald–Hartwig amination is a palladium-catalyzed cross-coupling reaction that forms carbon–nitrogen bonds by coupling aryl (or vinyl) halides with amines, widely used in the synthesis of pharmaceuticals and fine chemicals.
  • D. Corey–Nicolaou macrolactonization
    Corey–Nicolaou macrolactonization is a widely used organic synthesis reaction that forms large-ring lactones from hydroxy acids via an activated ester intermediate.
  • E. Heck reaction
    The Heck reaction is a palladium-catalyzed cross-coupling between alkenes and aryl or vinyl halides, widely used in organic synthesis to form carbon–carbon bonds.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Tsuji–Trost reactions
Triple: [Trost asymmetric allylic alkylation, belongsToClass, Tsuji–Trost reactions]
Generated description
Tsuji–Trost reactions are palladium-catalyzed allylic substitution processes widely used in organic synthesis to form carbon–carbon and carbon–heteroatom bonds with high regio- and stereocontrol.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Tsuji–Trost reactions
Target entity description: Tsuji–Trost reactions are palladium-catalyzed allylic substitution processes widely used in organic synthesis to form carbon–carbon and carbon–heteroatom bonds with high regio- and stereocontrol.
  • A. Eschenmoser sulfide contraction
    Eschenmoser sulfide contraction is an organic rearrangement reaction that converts certain sulfur-containing intermediates into carbonyl compounds, widely used in complex molecule and natural product synthesis.
  • B. Stork enamine reaction
    The Stork enamine reaction is a key carbon–carbon bond-forming method in organic chemistry that uses enamines as nucleophiles to alkylate or acylate carbonyl compounds in a controlled, selective way.
  • C. Buchwald–Hartwig amination
    The Buchwald–Hartwig amination is a palladium-catalyzed cross-coupling reaction that forms carbon–nitrogen bonds by coupling aryl (or vinyl) halides with amines, widely used in the synthesis of pharmaceuticals and fine chemicals.
  • D. Corey–Nicolaou macrolactonization
    Corey–Nicolaou macrolactonization is a widely used organic synthesis reaction that forms large-ring lactones from hydroxy acids via an activated ester intermediate.
  • E. Heck reaction
    The Heck reaction is a palladium-catalyzed cross-coupling between alkenes and aryl or vinyl halides, widely used in organic synthesis to form carbon–carbon bonds.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d88393905081908d00a86b99996ac8 completed April 10, 2026, 4:58 a.m.
NER Named-entity recognition batch_69e3b2ca46f88190b56e81d75012496c completed April 18, 2026, 4:35 p.m.
NED1 Entity disambiguation (via context triple) batch_6a00ab16a13081908427d4f253cb14fa completed May 10, 2026, 3:58 p.m.
NEDg Description generation batch_6a00ab8a416c819097ed3d6c915ac373 completed May 10, 2026, 4 p.m.
NED2 Entity disambiguation (via description) batch_6a00ac301f188190ae25d5ae7a39eb34 completed May 10, 2026, 4:02 p.m.
Created at: April 10, 2026, 5:22 a.m.