Tsuji–Trost reactions
E1233134
UNEXPLORED
Tsuji–Trost reactions are palladium-catalyzed allylic substitution processes widely used in organic synthesis to form carbon–carbon and carbon–heteroatom bonds with high regio- and stereocontrol.
All labels observed (2)
| Label | Occurrences |
|---|---|
| Tsuji–Trost allylic substitution | 1 |
| Tsuji–Trost reactions canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T16803397 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Tsuji–Trost reactions Context triple: [Trost asymmetric allylic alkylation, belongsToClass, Tsuji–Trost reactions]
-
A.
Eschenmoser sulfide contraction
Eschenmoser sulfide contraction is an organic rearrangement reaction that converts certain sulfur-containing intermediates into carbonyl compounds, widely used in complex molecule and natural product synthesis.
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B.
Stork enamine reaction
The Stork enamine reaction is a key carbon–carbon bond-forming method in organic chemistry that uses enamines as nucleophiles to alkylate or acylate carbonyl compounds in a controlled, selective way.
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C.
Buchwald–Hartwig amination
The Buchwald–Hartwig amination is a palladium-catalyzed cross-coupling reaction that forms carbon–nitrogen bonds by coupling aryl (or vinyl) halides with amines, widely used in the synthesis of pharmaceuticals and fine chemicals.
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D.
Corey–Nicolaou macrolactonization
Corey–Nicolaou macrolactonization is a widely used organic synthesis reaction that forms large-ring lactones from hydroxy acids via an activated ester intermediate.
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E.
Heck reaction
The Heck reaction is a palladium-catalyzed cross-coupling between alkenes and aryl or vinyl halides, widely used in organic synthesis to form carbon–carbon bonds.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Tsuji–Trost reactions Target entity description: Tsuji–Trost reactions are palladium-catalyzed allylic substitution processes widely used in organic synthesis to form carbon–carbon and carbon–heteroatom bonds with high regio- and stereocontrol.
-
A.
Eschenmoser sulfide contraction
Eschenmoser sulfide contraction is an organic rearrangement reaction that converts certain sulfur-containing intermediates into carbonyl compounds, widely used in complex molecule and natural product synthesis.
-
B.
Stork enamine reaction
The Stork enamine reaction is a key carbon–carbon bond-forming method in organic chemistry that uses enamines as nucleophiles to alkylate or acylate carbonyl compounds in a controlled, selective way.
-
C.
Buchwald–Hartwig amination
The Buchwald–Hartwig amination is a palladium-catalyzed cross-coupling reaction that forms carbon–nitrogen bonds by coupling aryl (or vinyl) halides with amines, widely used in the synthesis of pharmaceuticals and fine chemicals.
-
D.
Corey–Nicolaou macrolactonization
Corey–Nicolaou macrolactonization is a widely used organic synthesis reaction that forms large-ring lactones from hydroxy acids via an activated ester intermediate.
-
E.
Heck reaction
The Heck reaction is a palladium-catalyzed cross-coupling between alkenes and aryl or vinyl halides, widely used in organic synthesis to form carbon–carbon bonds.
- F. None of above. chosen
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
Tsuji–Trost allylic substitution