Statements (42)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antipsychotic medication
thioxanthene derivative |
| gptkbp:approvedBy |
1978
|
| gptkbp:ATCCode |
N05AF05
|
| gptkbp:brand |
Acuphase
Clopixol |
| gptkbp:CASNumber |
53772-83-1
|
| gptkbp:chemicalFormula |
C22H25ClN2OS
|
| gptkbp:contraindication |
gptkb:pheochromocytoma
coma CNS depression |
| gptkbp:developedBy |
gptkb:Lundbeck
|
| gptkbp:drugClass |
typical antipsychotic
|
| gptkbp:eliminationHalfLife |
19 days (depot)
20 hours (oral) |
| gptkbp:form |
zuclopenthixol acetate
zuclopenthixol decanoate zuclopenthixol dihydrochloride |
| https://www.w3.org/2000/01/rdf-schema#label |
zuclopenthixol
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
histamine H1 receptor antagonist
alpha-1 adrenergic receptor antagonist dopamine D1 and D2 receptor antagonist |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
gptkb:C_(Australia)
|
| gptkbp:proteinBinding |
98%
|
| gptkbp:routeOfAdministration |
oral
intramuscular injection |
| gptkbp:sideEffect |
gptkb:orthostatic_hypotension
constipation weight gain sedation dry mouth extrapyramidal symptoms |
| gptkbp:synonym |
cis(Z)-clopenthixol
|
| gptkbp:usedFor |
schizophrenia
psychosis acute mania |
| gptkbp:bfsParent |
gptkb:N05AH02
gptkb:CYP2D6_gene gptkb:N05AH03 |
| gptkbp:bfsLayer |
7
|