vaccine-induced immune thrombotic thrombocytopenia

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf medical condition
gptkbp:abbreviation VITT
gptkbp:causedBy gptkb:AstraZeneca_COVID-19_vaccine
gptkb:Johnson_&_Johnson_COVID-19_vaccine
vaccine
adenoviral vector vaccine
gptkbp:complication pulmonary embolism
deep vein thrombosis
cerebral venous sinus thrombosis
gptkbp:firstReported 2021
gptkbp:hasMechanism autoimmune response
antibodies against platelet factor 4
https://www.w3.org/2000/01/rdf-schema#label vaccine-induced immune thrombotic thrombocytopenia
gptkbp:mortalityRate up to 20%
gptkbp:onset 5 to 30 days after vaccination
gptkbp:riskFactor female sex
younger age
gptkbp:similarTo gptkb:heparin-induced_thrombocytopenia
gptkbp:symptom thrombosis
thrombocytopenia
blood clots
low platelet count
gptkbp:treatment corticosteroids
intravenous immunoglobulin
non-heparin anticoagulants
gptkbp:bfsParent gptkb:Cerebral_Venous_Thrombosis
gptkbp:bfsLayer 6