two-component regulatory system

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf biological regulatory system
gptkbp:composedOf response regulator
sensor kinase
gptkbp:discoveredIn 1980s
gptkbp:example CheA/CheY system
EnvZ/OmpR system
PhoR/PhoB system
gptkbp:foundIn gptkb:Bacteria
archaea
some eukaryotes
gptkbp:function signal transduction
environmental sensing
gene regulation
https://www.w3.org/2000/01/rdf-schema#label two-component regulatory system
gptkbp:mechanismOfAction phosphorylation
gptkbp:relatedTo antibiotic resistance
adaptation to environment
virulence regulation
gptkbp:response_regulator_activity modulates gene expression
receives phosphate group
gptkbp:sensor_kinase_activity autophosphorylation
gptkbp:bfsParent gptkb:EC_2.7.11.24
gptkbp:bfsLayer 7