|
gptkbp:instanceOf
|
gptkb:drug
gptkb:prostacyclin_analogue
|
|
gptkbp:approvalYear
|
2002
|
|
gptkbp:ATCCode
|
B01AC21
|
|
gptkbp:brand
|
gptkb:Orenitram
gptkb:Remodulin
gptkb:Tyvaso
|
|
gptkbp:CASNumber
|
81846-19-7
|
|
gptkbp:chemicalFormula
|
C23H34O5
|
|
gptkbp:contraindication
|
severe liver impairment
|
|
gptkbp:developer
|
gptkb:United_Therapeutics
|
|
gptkbp:drugClass
|
gptkb:vasodilator
|
|
gptkbp:eliminationHalfLife
|
4 hours
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
vasodilation
inhibition of platelet aggregation
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
390.51 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
subcutaneous
inhalation
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
headache
flushing
pain at infusion site
|
|
gptkbp:status
|
FDA approved
|
|
gptkbp:synonym
|
UT-15
|
|
gptkbp:usedFor
|
pulmonary arterial hypertension
|
|
gptkbp:bfsParent
|
gptkb:Lyumjev
gptkb:Orenitram
gptkb:Remodulin
gptkb:Tyvaso
gptkb:LIQ861
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
treprostinil
|