|
gptkbp:instanceOf
|
gptkb:antifungal_medication
|
|
gptkbp:ATCCode
|
D01AE15
|
|
gptkbp:brand
|
gptkb:Lamisil
gptkb:Terbinex
|
|
gptkbp:CASNumber
|
78628-80-5
|
|
gptkbp:chemicalFormula
|
C21H25N
|
|
gptkbp:contraindication
|
chronic or active liver disease
|
|
gptkbp:discoveredBy
|
gptkb:Novartis
|
|
gptkbp:drugClass
|
allylamine antifungal
|
|
gptkbp:eliminationHalfLife
|
36 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:IUPACName
|
(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits squalene epoxidase
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
291.44 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
oral
topical
|
|
gptkbp:sideEffect
|
headache
rash
gastrointestinal upset
taste disturbance
liver enzyme elevation
|
|
gptkbp:usedFor
|
treatment of fungal infections
treatment of athlete's foot
treatment of jock itch
treatment of ringworm
treatment of onychomycosis
|
|
gptkbp:year_of_approval
|
1991
|
|
gptkbp:bfsParent
|
gptkb:Osurnia
gptkb:Lamisil
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
terbinafine
|