Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antifungal medication
|
| gptkbp:ATCCode |
D01AE15
|
| gptkbp:brand |
gptkb:Lamisil
gptkb:Terbinex |
| gptkbp:CASNumber |
78628-80-5
|
| gptkbp:chemicalFormula |
C21H25N
|
| gptkbp:contraindication |
chronic or active liver disease
|
| gptkbp:discoveredBy |
gptkb:Novartis
|
| gptkbp:drugClass |
allylamine antifungal
|
| gptkbp:eliminationHalfLife |
36 hours
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
terbinafine
|
| gptkbp:IUPACName |
(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits squalene epoxidase
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
291.44 g/mol
|
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:routeOfAdministration |
oral
topical |
| gptkbp:sideEffect |
headache
rash gastrointestinal upset taste disturbance liver enzyme elevation |
| gptkbp:usedFor |
treatment of fungal infections
treatment of athlete's foot treatment of jock itch treatment of ringworm treatment of onychomycosis |
| gptkbp:year_of_approval |
1991
|
| gptkbp:bfsParent |
gptkb:Lamisil
|
| gptkbp:bfsLayer |
5
|