systemic lupus erythematosus in children

GPTKB entity

Statements (51)
Predicate Object
gptkbp:instanceOf gptkb:disease
autoimmune disease
gptkbp:affects gptkb:skin
adolescents
children
heart
lungs
central nervous system
kidneys
joints
multiple organ systems
gptkbp:alsoKnownAs childhood-onset SLE
gptkbp:causedBy unknown
gptkbp:complication infections
cardiac involvement
lupus nephritis
central nervous system involvement
gptkbp:diagnosedBy gptkb:ANA_test
laboratory tests
clinical criteria
anti-dsDNA antibodies
complement levels
https://www.w3.org/2000/01/rdf-schema#label systemic lupus erythematosus in children
gptkbp:mortalityRate higher than adult-onset SLE
gptkbp:onset childhood
adolescence
gptkbp:pathology immune complex deposition
chronic inflammation
autoantibody production
gptkbp:prevalence rare
more common in females
higher prevalence in African, Asian, and Hispanic populations
gptkbp:prognosis variable
worse than adult-onset SLE
gptkbp:riskFactor genetic predisposition
ethnic background
female sex
gptkbp:symptom fever
fatigue
joint pain
hair loss
photosensitivity
skin rash
oral ulcers
kidney involvement
gptkbp:treatment corticosteroids
immunosuppressive drugs
biologic agents
hydroxychloroquine
gptkbp:bfsParent gptkb:Department_of_Pediatric_Rheumatology
gptkbp:bfsLayer 7