systemic lupus erythematosus in children
GPTKB entity
Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:autoimmune_disease
gptkb:disease |
| gptkbp:affects |
gptkb:skin
adolescents children heart lungs central nervous system kidneys joints multiple organ systems |
| gptkbp:alsoKnownAs |
childhood-onset SLE
|
| gptkbp:causedBy |
gptkb:unknown
|
| gptkbp:complication |
infections
cardiac involvement lupus nephritis central nervous system involvement |
| gptkbp:diagnosedBy |
gptkb:ANA_test
laboratory tests clinical criteria anti-dsDNA antibodies complement levels |
| gptkbp:mortalityRate |
higher than adult-onset SLE
|
| gptkbp:onset |
childhood
adolescence |
| gptkbp:pathology |
immune complex deposition
chronic inflammation autoantibody production |
| gptkbp:prevalence |
rare
more common in females higher prevalence in African, Asian, and Hispanic populations |
| gptkbp:prognosis |
variable
worse than adult-onset SLE |
| gptkbp:riskFactor |
genetic predisposition
ethnic background female sex |
| gptkbp:symptom |
fever
fatigue joint pain hair loss photosensitivity skin rash oral ulcers kidney involvement |
| gptkbp:treatment |
corticosteroids
immunosuppressive drugs biologic agents hydroxychloroquine |
| gptkbp:bfsParent |
gptkb:Department_of_Pediatric_Rheumatology
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
systemic lupus erythematosus in children
|