|
gptkbp:instanceOf
|
gptkb:drug
sucrose sulfate-aluminum complex
|
|
gptkbp:approvedBy
|
1981 (US)
|
|
gptkbp:ATCCode
|
A02BX02
|
|
gptkbp:availableOn
|
gptkb:tablet
oral suspension
|
|
gptkbp:bioavailability
|
<5%
|
|
gptkbp:brand
|
Carafate
Sulcrate
|
|
gptkbp:CASNumber
|
54182-58-0
|
|
gptkbp:category
|
gastrointestinal agent
antiulcer agent
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
hypersensitivity to sucralfate
|
|
gptkbp:discoveredBy
|
gptkb:Merck_&_Co.
|
|
gptkbp:eliminationHalfLife
|
6-20 hours (aluminum component)
|
|
gptkbp:excretion
|
urine (minor)
feces (major)
|
|
gptkbp:hasMolecularFormula
|
C12H54Al16O75S8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
sucralfate
|
|
gptkbp:interactsWith
|
gptkb:fluoroquinolones
gptkb:phenytoin
gptkb:digoxin
thyroid hormones
tetracyclines
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
binds to ulcer sites
forms a protective barrier on ulcers
|
|
gptkbp:metabolism
|
not significantly metabolized
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
constipation
dry mouth
gastric discomfort
|
|
gptkbp:solubility
|
insoluble in water
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:usedFor
|
prevention of stress ulcers
treatment of duodenal ulcers
treatment of gastric ulcers
|
|
gptkbp:bfsParent
|
gptkb:drug-induced_esophagitis
gptkb:A02BC02
|
|
gptkbp:bfsLayer
|
7
|