sporadic inclusion body myositis
GPTKB entity
Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
inflammatory myopathy |
| gptkbp:abbreviation |
sIBM
|
| gptkbp:affects |
gptkb:skeletal_muscle
quadriceps pharyngeal muscles finger flexors |
| gptkbp:affectsMore |
men
|
| gptkbp:associatedWith |
inclusion bodies
endomysial inflammation rimmed vacuoles |
| gptkbp:causedBy |
unknown
|
| gptkbp:complication |
falls
dysphagia loss of mobility |
| gptkbp:diagnosedBy |
electromyography
muscle biopsy blood tests |
| gptkbp:differentialDiagnosis |
amyotrophic lateral sclerosis
muscular dystrophy polymyositis |
| gptkbp:field |
neurology
rheumatology |
| gptkbp:firstDescribed |
1971
|
| gptkbp:hasGeneticComponent |
unknown
|
| https://www.w3.org/2000/01/rdf-schema#label |
sporadic inclusion body myositis
|
| gptkbp:ICD-10_code |
G72.4
|
| gptkbp:MeSH_ID |
D020526
|
| gptkbp:notResponsiveTo |
immunosuppressive therapy
corticosteroids |
| gptkbp:OMIM |
147421
|
| gptkbp:onset |
adulthood
|
| gptkbp:pathology |
protein aggregates
T-cell infiltration cytoplasmic inclusions |
| gptkbp:prevalence |
rare
|
| gptkbp:progression |
slowly progressive
|
| gptkbp:riskFactor |
male sex
age over 50 |
| gptkbp:symptom |
difficulty swallowing
muscle weakness muscle wasting |
| gptkbp:treatment |
occupational therapy
physical therapy assistive devices no effective drug therapy |
| gptkbp:bfsParent |
gptkb:inclusion_body_myopathy
|
| gptkbp:bfsLayer |
7
|