sodium zirconium cyclosilicate

URI: https://gptkb.org/entity/sodium_zirconium_cyclosilicate
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkb:drug
gptkbp:approvalYear 2018
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
gptkbp:ATCCode V03AE10
gptkbp:brand gptkb:Lokelma
gptkbp:CASNumber 2077249-00-4
gptkbp:chemicalFormula Na12[(ZrO)2Si3O9]·xH2O
gptkbp:color white
gptkbp:contraindication gptkb:bowel_obstruction
severe constipation
gptkbp:developer ZS Pharma
gptkbp:drugClass potassium-removing agent
gptkbp:eliminatedIn feces
gptkbp:flavor odorless, tasteless
gptkbp:form powder for oral suspension
gptkbp:halfLife not systemically absorbed
https://www.w3.org/2000/01/rdf-schema#label sodium zirconium cyclosilicate
gptkbp:interactsWith other oral medications (may bind them)
gptkbp:legalStatus prescription only
gptkbp:marketingAuthorizationHolder gptkb:AstraZeneca
gptkbp:mechanismOfAction potassium binder
gptkbp:molecularWeight approx. 2,000 g/mol
gptkbp:pregnancyCategory not assigned (consult physician)
gptkbp:routeOfAdministration oral
gptkbp:sideEffect gastrointestinal discomfort
edema
hypokalemia
gptkbp:storage store below 30°C
gptkbp:usedFor treatment of hyperkalemia
gptkbp:bfsParent gptkb:Lokelma
gptkbp:bfsLayer 7