sodium phenylbutyrate

GPTKB entity

Statements (44)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkb:drug
gptkbp:administeredBy gptkb:tablet
oral solution
gptkbp:approvedBy gptkb:FDA
gptkb:EMA
gptkbp:ATCCode A16AX03
gptkbp:CASNumber 1716-12-7
gptkbp:chemicalFormula C10H11NaO2
gptkbp:discoveredBy 20th century
gptkbp:eliminationHalfLife 0.8-1 hour
gptkbp:excretion urine
gptkbp:has_trade_name gptkb:Buphenyl
gptkb:Ravicti
gptkbp:hasInChIKey QWESDIXLSGZNPB-UHFFFAOYSA-M
gptkbp:hasSMILES C1=CC=C(C=C1)CCCC(=O)[O-].[Na+]
gptkbp:hasUNII H8A007M85H
https://www.w3.org/2000/01/rdf-schema#label sodium phenylbutyrate
gptkbp:is_salt_of phenylbutyric acid
gptkbp:IUPACName sodium 4-phenylbutanoate
gptkbp:KEGGID gptkb:D08402
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction histone deacetylase inhibitor
ammonia scavenger
gptkbp:meltingPoint 285 °C
gptkbp:metabolism phenylacetate
gptkbp:molecularWeight 186.18 g/mol
gptkbp:pregnancyCategory C (US)
gptkbp:PubChem_CID 4720
4558
CHEMBL1201
DB00544
CHEBI:9120
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
vomiting
loss of appetite
body odor
menstrual irregularities
gptkbp:usedFor gptkb:urea_cycle_disorders
amyotrophic lateral sclerosis
spinal muscular atrophy
gptkbp:bfsParent gptkb:Buphenyl
gptkbp:bfsLayer 8