|
gptkbp:instanceOf
|
gptkb:drug
muscle relaxant
neuromuscular-blocking drug
|
|
gptkbp:antidote
|
gptkb:neostigmine
gptkb:sugammadex
|
|
gptkbp:ATCCode
|
gptkb:M03AC09
|
|
gptkbp:brand
|
gptkb:Esmeron
gptkb:Zemuron
|
|
gptkbp:CASNumber
|
gptkb:119302-91-9
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
hepatic impairment
hypersensitivity to rocuronium
|
|
gptkbp:discoveredBy
|
gptkb:Organon
|
|
gptkbp:duration
|
30-60 minutes
|
|
gptkbp:eliminationHalfLife
|
1.4-2.4 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C32H53BrN2O4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
rocuronium bromide
|
|
gptkbp:introducedIn
|
1994
|
|
gptkbp:KEGGID
|
D08413
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:MeSH_ID
|
D019695
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:onset
|
1-2 minutes
|
|
gptkbp:pregnancyCategory
|
B (US)
B1 (Australia)
|
|
gptkbp:proteinBinding
|
30-40%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201197
5311068
4470732
DB00728
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
allergic reaction
hypotension
tachycardia
bronchospasm
|
|
gptkbp:synonym
|
1-[17β-Acetoxy-3α-hydroxy-2β-(morpholino)-5α-androstan-16β-yl]-1-methylpiperidinium bromide
|
|
gptkbp:UNII
|
601B7M973T
|
|
gptkbp:usedFor
|
intensive care
facilitation of tracheal intubation
skeletal muscle relaxation during surgery
|
|
gptkbp:bfsParent
|
gptkb:rocuronium
|
|
gptkbp:bfsLayer
|
6
|