ribonuclease A superfamily

URI: https://gptkb.org/entity/ribonuclease_A_superfamily
GPTKB entity
Statements (43)
Predicate Object
gptkbp:instanceOf superfamily
gptkbp:activity ribonuclease activity
gptkbp:alsoKnownAs RNase A superfamily
gptkbp:characterizedBy disulfide bonds
conserved catalytic triad
gptkbp:contains gptkb:ribonuclease_A
gptkb:eosinophil-derived_neurotoxin
gptkb:eosinophil_cationic_protein
gptkb:angiogenin
gptkbp:discoveredBy Richard S. Stein
gptkbp:EC_number 3.1.27.5
gptkbp:evolvesFrom vertebrate ancestor
gptkbp:firstDescribed 1940s
gptkbp:foundIn vertebrates
gptkbp:function catalyzes RNA degradation
gptkbp:GO GO:0004540
https://www.w3.org/2000/01/rdf-schema#label ribonuclease A superfamily
gptkbp:InterPro IPR001427
gptkbp:PDB gptkb:1FS3
gptkbp:proteinFamily gptkb:RNASE1
gptkb:RNASE3
RNASE2
PF00074
RNASE10
RNASE11
RNASE12
RNASE13
RNASE14
RNASE15
RNASE4
RNASE5
RNASE6
RNASE7
RNASE8
RNASE9
gptkbp:relatedTo immune defense
angiogenesis
host defense
antimicrobial activity
gptkbp:structure alpha+beta fold
gptkbp:UniProtID P61823
gptkbp:bfsParent gptkb:Eosinophil_Cationic_Protein
gptkbp:bfsLayer 7