retinal pigment epithelium

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf adipose tissue
cell layer
gptkbp:adjacentTo gptkb:Bruch's_membrane
photoreceptor layer
gptkbp:cellType simple cuboidal epithelium
gptkbp:color dark brown
gptkbp:contains melanin
gptkbp:develops_from outer layer of optic cup
gptkbp:forms_part_of gptkb:blood-retina_barrier
gptkbp:function absorbs scattered light
forms blood-retina barrier
phagocytosis of photoreceptor outer segments
removes waste products
supports photoreceptors
transports nutrients to retina
https://www.w3.org/2000/01/rdf-schema#label retinal pigment epithelium
gptkbp:involvedIn visual cycle
retinoid metabolism
gptkbp:location eye
between neural retina and choroid
gptkbp:relatedTo gptkb:Stargardt_disease
age-related macular degeneration
retinitis pigmentosa
gptkbp:secretes growth factors
immunosuppressive factors
gptkbp:supplies choroidal blood vessels
gptkbp:bfsParent gptkb:MITF
gptkb:RPE65
gptkb:OCA2
gptkb:LRAT_gene
gptkb:RPE65_gene
gptkb:11-cis-retinal
gptkbp:bfsLayer 7