protein secondary structure prediction

GPTKB entity

Statements (40)
Predicate Object
gptkbp:instanceOf scientific research
gptkbp:accuracy ~80% for three-state prediction
gptkbp:application protein engineering
drug design
functional annotation
gptkbp:benchmark_dataset gptkb:CASP
gptkb:CB513
gptkbp:challenge disordered regions
low sequence similarity
gptkbp:common_structures coil
beta sheet
alpha helix
gptkbp:database gptkb:Protein_Data_Bank_(PDB)
gptkb:UniProt
gptkbp:field structural biology
bioinformatics
gptkbp:first_method gptkb:Chou-Fasman_algorithm
gptkb:Garnier-Osguthorpe-Robson_(GOR)_method
gptkbp:goal predict local structures of proteins
https://www.w3.org/2000/01/rdf-schema#label protein secondary structure prediction
gptkbp:improves multiple sequence alignment
gptkbp:input amino acid sequence
gptkbp:method gptkb:machine_learning
gptkb:hidden_Markov_models
neural networks
statistical analysis
support vector machines
gptkbp:notableTool gptkb:JPred
gptkb:PSIPRED
gptkb:SPIDER3
gptkb:Porter
gptkbp:output secondary structure assignment
gptkbp:relatedConcept protein folding
protein tertiary structure prediction
gptkbp:relatedTo computational biology
molecular biology
gptkbp:uses evolutionary information
position-specific scoring matrices
gptkbp:bfsParent gptkb:Markov_chain
gptkbp:bfsLayer 5