pre-exposure prophylaxis (PrEP)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	medical intervention
gptkbp:abbreviation	gptkb:PrEP
gptkbp:administeredBy	HIV-negative individuals
gptkbp:alternativeDrug	gptkb:cabotegravir
gptkbp:alternativeTo	long-acting injectable PrEP
gptkbp:approvalYear	2012
gptkbp:approvedBy	gptkb:U.S._Food_and_Drug_Administration
gptkbp:commonDrug	gptkb:tenofovir_disoproxil_fumarate emtricitabine
gptkbp:contraindication	severe renal impairment HIV-positive status
gptkbp:effect	over 90% when taken as prescribed
gptkbp:frequency	daily
https://www.w3.org/2000/01/rdf-schema#label	pre-exposure prophylaxis (PrEP)
gptkbp:involves	antiretroviral drugs
gptkbp:notEffectiveAgainst	pregnancy other sexually transmitted infections
gptkbp:recommendation	gptkb:Centers_for_Disease_Control_and_Prevention gptkb:World_Health_Organization
gptkbp:reduces	HIV infection
gptkbp:requires	adherence to daily regimen medical follow-up regular HIV testing
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	nausea headache kidney function changes
gptkbp:targetAudience	gptkb:men_who_have_sex_with_men people who inject drugs heterosexual individuals at high risk
gptkbp:usedFor	HIV prevention
gptkbp:bfsParent	gptkb:HIV/AIDS
gptkbp:bfsLayer	4