pituitary adenylate cyclase-activating polypeptide (PACAP)

URI: https://gptkb.org/entity/pituitary_adenylate_cyclase-activating_polypeptide_(PACAP)
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:peptide
gptkbp:discoveredIn 1989
gptkbp:encodedBy gptkb:ADCYAP1_gene
gptkbp:foundIn gptkb:adrenal_gland
brain
gastrointestinal tract
pancreas
testes
gptkbp:function gptkb:growth_factor
gptkb:vasodilator
gptkb:neurotransmitter
regulates hormone secretion
stimulates adenylate cyclase activity
gptkbp:hasIsoform gptkb:PACAP-27
gptkb:PACAP-38
gptkbp:HGNC_ID 240
gptkbp:involvedIn stress response
neuroprotection
immune modulation
circadian rhythm regulation
migraine pathophysiology
gptkbp:length 27 amino acids (PACAP-27)
38 amino acids (PACAP-38)
gptkbp:locatedOnChromosome gptkb:18p11.32
gptkbp:orthologIn gptkb:VIP_family_peptides
gptkbp:recipient gptkb:PAC1_receptor
gptkb:VPAC1_receptor
gptkb:VPAC2_receptor
gptkbp:relatedTo gptkb:vasoactive_intestinal_peptide_(VIP)
gptkbp:structure polypeptide
gptkbp:UniProtID P18509
gptkbp:bfsParent gptkb:enterochromaffin-like_cells
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label pituitary adenylate cyclase-activating polypeptide (PACAP)