Statements (49)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
natural product |
| gptkbp:antidote |
no specific antidote
|
| gptkbp:aroma |
odorless
|
| gptkbp:category |
natural product
marine toxin biotoxin non-protein toxin polyether toxin |
| gptkbp:chemicalFormula |
C129H223N3O54
|
| gptkbp:color |
colorless
|
| gptkbp:discoveredBy |
gptkb:Richard_Moore
gptkb:Paul_Scheuer |
| gptkbp:discoveredIn |
1971
|
| gptkbp:foundIn |
Ostreopsis dinoflagellates
Palythoa toxica marine zoanthids |
| https://www.w3.org/2000/01/rdf-schema#label |
palytoxin
|
| gptkbp:isomerOf |
many stereoisomers
|
| gptkbp:IUPACName |
(1R,2R,3E,5S,6R,7S,8R,9S,10R,11R,12R,13R,14R,15R,16R,17R,18R,19R,20R,21R,22R,23R,24R,25R,26R,27R,28R,29R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R,57R,58R,59R,60R,61R,62R,63R,64R,65R,66R,67R,68R,69R,70R,71R,72R,73R,74R,75R,76R,77R,78R,79R,80R,81R,82R,83R,84R,85R,86R,87R,88R,89R,90R,91R,92R,93R,94R,95R,96R,97R,98R,99R,100R,101R,102R,103R,104R,105R,106R,107R,108R,109R,110R,111R,112R,113R,114R,115R,116R,117R,118R,119R,120R,121R,122R,123R,124R,125R,126R,127R,128R,129R)-129-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,7,9,11,13,15,17,19,21,23,25,27,29,31,33,35,37,39,41,43,45,47,49,51,53,55,57,59,61,63,65,67,69,71,73,75,77,79,81,83,85,87,89,91,93,95,97,99,101,103,105,107,109,111,113,115,117,119,121,123,125,127-nonacontaheptacontane-2,4,6,8,10,12,14,16,18,20,22,24,26,28,30,32,34,36,38,40,42,44,46,48,50,52,54,56,58,60,62,64,66,68,70,72,74,76,78,80,82,84,86,88,90,92,94,96,98,100,102,104,106,108,110,112,114,116,118,120,122,124,126,128-tetraol
|
| gptkbp:KEGGID |
C10713
|
| gptkbp:LD50 |
0.15 μg/kg (mouse, intravenous)
|
| gptkbp:mechanismOfAction |
inhibits Na+/K+-ATPase
|
| gptkbp:MeSH_ID |
C030986
|
| gptkbp:molecularWeight |
2680.13 g/mol
|
| gptkbp:notableFor |
one of the most toxic non-protein substances
|
| gptkbp:PubChem_CID |
450277
CHEMBL108312 |
| gptkbp:relatedTo |
homopalytoxin
ostreocin-D palytoxin congeners |
| gptkbp:riskFactor |
causes severe poisoning
|
| gptkbp:routeOfExposure |
inhalation
ingestion skin contact |
| gptkbp:solubility |
water soluble
|
| gptkbp:stable |
unstable in light and heat
|
| gptkbp:symptom |
death
respiratory distress muscle weakness cardiac arrest hemolysis rhabdomyolysis |
| gptkbp:toxicity |
extremely toxic
|
| gptkbp:treatment |
supportive care
|
| gptkbp:UNII |
1X6RDW0F35
|
| gptkbp:uses |
biological research
|
| gptkbp:bfsParent |
gptkb:Zoantharia
|
| gptkbp:bfsLayer |
6
|