oral submucous fibrosis

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:disease
oral disease
gptkbp:affects esophagus
pharynx
soft palate
buccal mucosa
oral mucosa
retromolar area
gptkbp:age 20-40 years
gptkbp:associatedWith iron deficiency
nutritional deficiencies
vitamin B complex deficiency
gptkbp:cause oral cancer
gptkbp:characterizedBy burning sensation in mouth
progressive fibrosis of oral mucosa
restricted mouth opening
gptkbp:commonIn males
gptkbp:complication speech impairment
malignant transformation
difficulty in eating
gptkbp:diagnosedBy clinical examination
biopsy
histopathological analysis
gptkbp:firstDescribed 1952
J.J. Pindborg
gptkbp:histology atrophy of epithelium
inflammatory cell infiltration
subepithelial fibrosis
https://www.w3.org/2000/01/rdf-schema#label oral submucous fibrosis
gptkbp:ICD-10_code K13.2
gptkbp:prevalence gptkb:India
gptkb:South_Asia
gptkb:Southeast_Asia
gptkbp:prevention public health education
early diagnosis
avoidance of areca nut
gptkbp:progression irreversible in advanced stages
gptkbp:riskFactor genetic predisposition
tobacco use
betel quid chewing
areca nut chewing
gptkbp:symptom trismus
blanching of oral mucosa
loss of elasticity of oral mucosa
gptkbp:treatment physiotherapy
surgical intervention
cessation of areca nut
intralesional corticosteroids
gptkbp:bfsParent gptkb:Arecoline
gptkbp:bfsLayer 7