nonalcoholic steatohepatitis (NASH)

URI: https://gptkb.org/entity/nonalcoholic_steatohepatitis_(NASH)
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkb:liver_disease
gptkbp:affectsOrgan liver
gptkbp:associatedWith gptkb:cardiovascular_disease
insulin resistance
gptkbp:canBeAsymptomatic true
gptkbp:canProgressTo liver cancer
cirrhosis
liver fibrosis
gptkbp:cause liver failure
hepatocellular carcinoma
gptkbp:causedBy alcohol consumption
gptkbp:characterizedBy liver inflammation
fat accumulation in the liver
gptkbp:diagnosedBy liver biopsy
blood tests
imaging studies
gptkbp:firstDescribed 1980
https://www.w3.org/2000/01/rdf-schema#label nonalcoholic steatohepatitis (NASH)
gptkbp:ICD-10_code K75.81
gptkbp:partOf nonalcoholic fatty liver disease (NAFLD)
gptkbp:prevalence increasing worldwide
gptkbp:riskFactor gptkb:type_2_diabetes
gptkb:metabolic_syndrome
obesity
dyslipidemia
gptkbp:symptom fatigue
abdominal discomfort
gptkbp:treatment exercise
weight loss
diet modification
medications (under investigation)
gptkbp:bfsParent gptkb:Akero_Therapeutics
gptkb:Intercept_Pharmaceuticals
gptkbp:bfsLayer 7