Statements (34)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
histamine H2 receptor antagonist |
gptkbp:approvedBy |
1988
|
gptkbp:ATCCode |
A02BA04
|
gptkbp:brand |
Axid
|
gptkbp:CASNumber |
76963-41-2
|
gptkbp:chemicalClass |
thiazole
|
gptkbp:discoveredBy |
gptkb:Eli_Lilly_and_Company
|
gptkbp:eliminationHalfLife |
1-2 hours
|
gptkbp:excretion |
renal
|
gptkbp:hasMolecularFormula |
C12H21N5O2S2
|
https://www.w3.org/2000/01/rdf-schema#label |
nizatidine
|
gptkbp:KEGGID |
D08213
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
blocks H2 receptors in stomach
|
gptkbp:meltingPoint |
160-162°C
|
gptkbp:metabolism |
minimal hepatic
|
gptkbp:pregnancyCategory |
B (US)
|
gptkbp:PubChem_CID |
gptkb:CHEMBL1431
4884 4715 DB00586 |
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
diarrhea
dizziness fatigue headache |
gptkbp:UNII |
6X5848Q8FU
|
gptkbp:usedFor |
treatment of peptic ulcer disease
treatment of Zollinger-Ellison syndrome treatment of gastroesophageal reflux disease |
gptkbp:bfsParent |
gptkb:famotidine
gptkb:H2_blocker |
gptkbp:bfsLayer |
6
|