Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antineoplastic agent |
| gptkbp:chemicalFormula |
R1N(CONR2)NO
|
| gptkbp:contains_functional_group |
gptkb:urea
nitroso group |
| gptkbp:crosses_blood-brain_barrier |
yes
|
| gptkbp:discoveredBy |
1960s
|
| gptkbp:example |
gptkb:carmustine
gptkb:lomustine gptkb:streptozotocin fotemustine semustine |
| https://www.w3.org/2000/01/rdf-schema#label |
nitrosourea
|
| gptkbp:mechanismOfAction |
antineoplastic agent
|
| gptkbp:sideEffect |
nausea
vomiting myelosuppression |
| gptkbp:usedFor |
gptkb:cancer
leukemia multiple myeloma brain tumors |
| gptkbp:bfsParent |
gptkb:lomustine
gptkb:streptozotocin |
| gptkbp:bfsLayer |
7
|