|
gptkbp:instanceOf
|
gptkb:chemical_compound
anthelmintic drug
salicylanilide
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
P02DA01
|
|
gptkbp:brand
|
Fenasal
Niclocide
Yomesan
|
|
gptkbp:CASNumber
|
50-65-7
|
|
gptkbp:chemicalFormula
|
C13H8Cl2N2O4
|
|
gptkbp:color
|
yellow
|
|
gptkbp:discoveredBy
|
1958
|
|
gptkbp:excretion
|
feces
|
|
gptkbp:firstSynthesized
|
gptkb:Bayer
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
niclosamide
|
|
gptkbp:includes
|
gptkb:World_Health_Organization's_List_of_Essential_Medicines
|
|
gptkbp:IUPACName
|
5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
|
|
gptkbp:KEGGID
|
D00432
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits oxidative phosphorylation in mitochondria
|
|
gptkbp:meltingPoint
|
225–230 °C
|
|
gptkbp:metabolism
|
minimal
|
|
gptkbp:molecularWeight
|
327.12 g/mol
|
|
gptkbp:notEffectiveAgainst
|
extraintestinal parasites
larval tapeworms
|
|
gptkbp:potential_research_use
|
antiviral drug
anticancer agent
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1431
4477
4322
DB06822
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
vomiting
abdominal pain
itching
rash
|
|
gptkbp:solubility
|
very low
|
|
gptkbp:UNII
|
EC20M1D68B
|
|
gptkbp:used_in
|
gptkb:Hymenolepis_nana
gptkb:Taenia_solium
gptkb:Diphyllobothrium_latum
gptkb:Taenia_saginata
|
|
gptkbp:used_in_veterinary_medicine
|
yes
|
|
gptkbp:usedFor
|
gptkb:entomologist
treatment of tapeworm infections
molluscicide
|
|
gptkbp:bfsParent
|
gptkb:Hymenolepis_nana
gptkb:Taeniasis
gptkb:Diphyllobothrium_latum
gptkb:Taenia_saginata
|
|
gptkbp:bfsLayer
|
7
|