|
gptkbp:instanceOf
|
gptkb:drug
eye drops
Rho kinase inhibitor
|
|
gptkbp:approvalYear
|
2017
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
S01EX05
|
|
gptkbp:brand
|
gptkb:Rhopressa
|
|
gptkbp:CASNumber
|
1254036-71-9
|
|
gptkbp:chemicalFormula
|
C28H35N3O5
|
|
gptkbp:contraindication
|
hypersensitivity to netarsudil
|
|
gptkbp:developedBy
|
gptkb:Aerie_Pharmaceuticals
|
|
gptkbp:form
|
0.02% ophthalmic solution
|
|
gptkbp:frequency
|
once daily in the evening
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
netarsudil
|
|
gptkbp:KEGGID
|
D10813
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
increases outflow of aqueous humor through trabecular meshwork
|
|
gptkbp:molecularWeight
|
509.6 g/mol
|
|
gptkbp:pregnancyCategory
|
Not assigned (US)
|
|
gptkbp:PubChem_CID
|
gptkb:DB13928
CHEMBL2103887
46215929
|
|
gptkbp:routeOfAdministration
|
topical (eye drops)
|
|
gptkbp:sideEffect
|
eye pain
conjunctival hyperemia
instillation site pain
corneal verticillata
|
|
gptkbp:UNII
|
KXJ3Q6XNWX
|
|
gptkbp:usedFor
|
treatment of ocular hypertension
treatment of open-angle glaucoma
|
|
gptkbp:bfsParent
|
gptkb:Rhopressa
gptkb:Rocklatan
|
|
gptkbp:bfsLayer
|
8
|