mucolipidosis type IV

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:lysosomal_storage_disease
gptkbp:diagnosedBy genetic testing
gptkbp:firstDescribed 1974
gptkbp:frequencyInAshkenaziJewishPopulation higher
gptkbp:ICD-10_code E75.0
gptkbp:inheritance autosomal recessive
gptkbp:mutationAssociatedWith gptkb:MCOLN1_gene
gptkbp:namedAfter lysosomal storage and mucolipin protein defect
gptkbp:OMIM 252650
gptkbp:onset infancy
gptkbp:otherName gptkb:ML4
gptkbp:prevalence rare
gptkbp:symptom gptkb:intellectual_disability
developmental delay
gastrointestinal problems
corneal clouding
muscle hypotonia
progressive vision loss
gptkbp:treatment supportive care
gptkbp:bfsParent gptkb:ML4
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label mucolipidosis type IV