|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvalYear
|
2003 (US)
2002 (EU)
|
|
gptkbp:approvedBy
|
gptkb:FDA
gptkb:EMA
|
|
gptkbp:ATCCode
|
A16AX06
|
|
gptkbp:brand
|
gptkb:Zavesca
|
|
gptkbp:CASNumber
|
72599-27-0
|
|
gptkbp:chemicalFormula
|
piperidine ring
|
|
gptkbp:contraindication
|
pregnancy
renal impairment
|
|
gptkbp:developer
|
gptkb:Actelion
|
|
gptkbp:drugClass
|
iminosugar
|
|
gptkbp:eliminationHalfLife
|
6-7 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C10H21NO4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
miglustat
|
|
gptkbp:KEGGID
|
D04813
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits glucosylceramide synthase
|
|
gptkbp:metabolism
|
not extensively metabolized
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
441314
CHEMBL1250
DB00419
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
diarrhea
tremor
weight loss
numbness
tingling
|
|
gptkbp:synonym
|
N-butyldeoxynojirimycin
|
|
gptkbp:UNII
|
8B1QWR724A
|
|
gptkbp:usedFor
|
gptkb:Niemann-Pick_disease_type_C
gptkb:Gaucher_disease_type_1
|
|
gptkbp:bfsParent
|
gptkb:Niemann-Pick_disease_type_C
gptkb:Zavesca
|
|
gptkbp:bfsLayer
|
7
|