metalloprotease

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName metalloendopeptidase
gptkbp:catalyzes hydrolysis of peptide bonds
gptkbp:cofactor metal ion
gptkbp:commonCofactor zinc
gptkbp:EC_number 3.4.24.-
gptkbp:example gptkb:matrix_metalloproteinase
gptkb:neprilysin
thermolysin
gptkbp:foundIn gptkb:Bacteria
animals
plants
gptkbp:function protein degradation
extracellular matrix remodeling
regulation of biological processes
gptkbp:inhibitedBy chelating agents
gptkbp:significance arthritis
cancer progression
bacterial pathogenesis
gptkbp:structure active site contains metal ion
gptkbp:bfsParent gptkb:protease
gptkbp:bfsLayer 6