Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
antipsychotic medication |
gptkbp:approvalYear |
2019
|
gptkbp:approvedBy |
gptkb:FDA
|
gptkbp:ATCCode |
N05AH06
|
gptkbp:brand |
Caplyta
|
gptkbp:CASNumber |
951376-59-1
|
gptkbp:chemicalClass |
isoquinolinone derivative
|
gptkbp:developer |
Intra-Cellular Therapies, Inc.
|
gptkbp:eliminationHalfLife |
18 hours
|
gptkbp:excretion |
urine
feces |
gptkbp:hasMolecularFormula |
C24H28FN3O
|
https://www.w3.org/2000/01/rdf-schema#label |
lumateperone
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
dopamine D2 receptor antagonist
serotonin 5-HT2A receptor antagonist dopamine D1 receptor modulator serotonin transporter inhibitor |
gptkbp:metabolism |
liver
|
gptkbp:pregnancyCategory |
Not assigned
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:sideEffect |
dizziness
weight gain dry mouth somnolence increased creatinine |
gptkbp:usedFor |
schizophrenia
bipolar depression |
gptkbp:bfsParent |
gptkb:N05AX
|
gptkbp:bfsLayer |
7
|