Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:drug |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
C10AX13
|
| gptkbp:brand |
gptkb:Juxtapid
|
| gptkbp:CASNumber |
182431-12-5
|
| gptkbp:contraindication |
pregnancy
moderate or severe liver impairment |
| gptkbp:developedBy |
gptkb:Aegerion_Pharmaceuticals
|
| gptkbp:eliminationHalfLife |
39.7 hours
|
| gptkbp:hasMolecularFormula |
C39H37NO4·CH4O3S
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
microsomal triglyceride transfer protein inhibitor
|
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
gptkb:X_(US)
|
| gptkbp:proteinBinding |
99.8%
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL2103837
11274304 DB08827 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
gastrointestinal disturbance
liver enzyme elevation |
| gptkbp:UNII |
8Y7I1YV5TP
|
| gptkbp:usedFor |
gptkb:homozygous_familial_hypercholesterolemia
|
| gptkbp:bfsParent |
gptkb:Juxtapid
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
lomitapide mesylate
|