|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:drug
|
|
gptkbp:approvalYear
|
2012
|
|
gptkbp:ATCCode
|
gptkb:C10AX09
|
|
gptkbp:brand
|
gptkb:Juxtapid
Lojuxta
|
|
gptkbp:CASNumber
|
182431-12-5
|
|
gptkbp:contraindication
|
pregnancy
moderate or severe liver impairment
|
|
gptkbp:developer
|
gptkb:Aegerion_Pharmaceuticals
|
|
gptkbp:eliminationHalfLife
|
39.7 hours
|
|
gptkbp:hasMolecularFormula
|
C39H37NO2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
lomitapide
|
|
gptkbp:KEGGID
|
D09913
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
microsomal triglyceride transfer protein inhibitor
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
552.7 g/mol
|
|
gptkbp:pregnancyCategory
|
gptkb:X_(US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL2103836
11274304
DB08827
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
gastrointestinal disturbance
liver enzyme elevation
|
|
gptkbp:status
|
FDA approved
EMA approved
|
|
gptkbp:synonym
|
gptkb:BMS-201038
|
|
gptkbp:UNII
|
K8L4A4GZ6D
|
|
gptkbp:usedFor
|
gptkb:homozygous_familial_hypercholesterolemia
|
|
gptkbp:bfsParent
|
gptkb:MTTP_gene
|
|
gptkbp:bfsLayer
|
6
|