Statements (54)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:hospital
|
gptkbp:bfsLayer |
5
|
gptkbp:bfsParent |
gptkb:Icy_Hot_Lidocaine
|
gptkbp:activities |
sodium channel blocker
|
gptkbp:approves |
1948
|
gptkbp:brand |
gptkb:Lidoderm
gptkb:Xylocaine |
gptkbp:contraindication |
severe liver disease
methemoglobinemia hypersensitivity to amide anesthetics severe heart block |
gptkbp:dissolved |
soluble in water
soluble in alcohol |
gptkbp:excretion |
urine
|
gptkbp:formulation |
gptkb:spacecraft
gptkb:software_framework gptkb:tablet gptkb:skincare_product spray |
https://www.w3.org/2000/01/rdf-schema#label |
lidocaine hydrochloride
|
gptkbp:indication |
minor surgical procedures
dental procedures nerve blocks epidural anesthesia |
gptkbp:ingredients |
C14 H22 N2 O. H Cl
|
gptkbp:is_atype_of |
N01 B B02
|
gptkbp:is_used_for |
local anesthesia
ventricular arrhythmias |
gptkbp:legal_issue |
prescription only
|
gptkbp:level |
7.9
|
gptkbp:lifespan |
1.5 to 2 hours
|
gptkbp:manager |
injection
topical |
gptkbp:metabolism |
liver
|
gptkbp:pharmacokinetics |
rapid onset of action
highly protein bound crosses blood-brain barrier crosses placenta duration of action 1-2 hours |
gptkbp:products |
gptkb:articaine
gptkb:bupivacaine gptkb:ropivacaine gptkb:lidocaine prilocaine |
gptkbp:side_effect |
dizziness
nausea allergic reactions cardiac arrest seizures respiratory depression hypotension tinnitus |
gptkbp:type_of |
6108-05-0
|
gptkbp:weight |
288.82 g/mol
|