|
gptkbp:instanceOf
|
gptkb:chemical_compound
bisphosphonate
|
|
gptkbp:approvalYear
|
2003
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
M05BA06
|
|
gptkbp:brand
|
gptkb:Boniva
gptkb:Bondronat
|
|
gptkbp:CASNumber
|
114084-78-5
|
|
gptkbp:discoveredBy
|
gptkb:Roche
|
|
gptkbp:eliminationHalfLife
|
10-60 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:hasMolecularFormula
|
C9H23NO7P2
|
|
gptkbp:hasSMILES
|
C(CN)(P(=O)(O)O)C(O)(P(=O)(O)O)C(=O)O
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ibandronic acid
|
|
gptkbp:KEGGID
|
D08013
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits osteoclast-mediated bone resorption
|
|
gptkbp:molecularWeight
|
319.23 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201197
54813
DB00710
60854
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
gastrointestinal upset
musculoskeletal pain
osteonecrosis of the jaw
|
|
gptkbp:UNII
|
8KQ660G10Z
|
|
gptkbp:usedFor
|
treatment of osteoporosis
treatment of metastatic bone disease
|
|
gptkbp:bfsParent
|
gptkb:M05BA08
|
|
gptkbp:bfsLayer
|
6
|