Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
bisphosphonate |
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
M05BA06
|
| gptkbp:brand |
gptkb:Boniva
gptkb:Bondronat |
| gptkbp:CASNumber |
114084-78-5
|
| gptkbp:chemicalFormula |
C9H23NO7P2
|
| gptkbp:contraindication |
severe renal impairment
hypocalcemia |
| gptkbp:discoveredBy |
gptkb:Roche
|
| gptkbp:eliminationHalfLife |
10-60 hours
|
| gptkbp:excretion |
renal
|
| https://www.w3.org/2000/01/rdf-schema#label |
ibandronate
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits osteoclast-mediated bone resorption
|
| gptkbp:metabolism |
not metabolized
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
gastrointestinal upset
musculoskeletal pain osteonecrosis of the jaw |
| gptkbp:usedFor |
treatment of osteoporosis
prevention of osteoporosis |
| gptkbp:bfsParent |
gptkb:bisphosphonates
|
| gptkbp:bfsLayer |
6
|