galactosemia

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:genetic_disorder
gptkb:inborn_error_of_metabolism
gptkbp:affects galactose metabolism
gptkbp:causedBy mutation in GALE gene
mutation in GALK1 gene
mutation in GALT gene
gptkbp:complication kidney failure
sepsis
liver damage
ovarian failure
gptkbp:diagnosedBy genetic testing
enzyme assay
newborn screening
gptkbp:firstDescribed 1935
gptkbp:ICD-10_code E74.2
gptkbp:inheritance autosomal recessive
gptkbp:namedAfter galactose
gptkbp:OMIM 230400
gptkbp:prevalence 1 in 30,000 to 60,000 births
gptkbp:symptom gptkb:intellectual_disability
gptkb:cataracts
vomiting
jaundice
failure to thrive
hepatomegaly
gptkbp:treatment galactose-free diet
gptkbp:bfsParent gptkb:Newborn_Screening
gptkb:Nutritional_and_Metabolic_Diseases
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label galactosemia

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