|
gptkbp:instanceOf
|
anthelmintic drug
benzimidazole
|
|
gptkbp:ATCCode
|
P02CA05
|
|
gptkbp:CASNumber
|
31430-15-6
|
|
gptkbp:chemicalFormula
|
C16H12FN3O3
|
|
gptkbp:contraindication
|
pregnancy
hypersensitivity to benzimidazoles
|
|
gptkbp:discoveredBy
|
gptkb:Janssen_Pharmaceutica
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasSMILES
|
COC(=O)Nc1nc2ccc(F)cc2[nH]1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
flubendazole
|
|
gptkbp:introducedIn
|
1972
|
|
gptkbp:IUPACName
|
methyl N-(6-fluoro-1H-benzimidazol-2-yl)carbamate
|
|
gptkbp:KEGGID
|
D04110
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits tubulin polymerization
|
|
gptkbp:meltingPoint
|
205–210 °C
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
313.29 g/mol
|
|
gptkbp:pregnancyCategory
|
gptkb:C_(Australia)
|
|
gptkbp:PubChem_CID
|
3355
CHEMBL1402
DB08974
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
vomiting
diarrhea
abdominal pain
|
|
gptkbp:synonym
|
Fluvermal
|
|
gptkbp:UNII
|
Q1J8A4K29N
|
|
gptkbp:used_in_veterinary_medicine
|
yes
|
|
gptkbp:usedFor
|
treatment of parasitic worm infestations
treatment of gastrointestinal nematodes
|
|
gptkbp:bfsParent
|
gptkb:fenbendazole
|
|
gptkbp:bfsLayer
|
7
|