familial hypercholesterolemia (mouse model)
GPTKB entity
Statements (16)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
mouse model
|
| gptkbp:exhibits |
elevated plasma cholesterol
atherosclerotic plaque formation increased LDL |
| gptkbp:hasGeneticModification |
ApoE knockout
LDLR knockout |
| gptkbp:hasModel |
gptkb:familial_hypercholesterolemia
|
| https://www.w3.org/2000/01/rdf-schema#label |
familial hypercholesterolemia (mouse model)
|
| gptkbp:relatedTo |
human familial hypercholesterolemia
|
| gptkbp:species |
gptkb:Mus_musculus
|
| gptkbp:usedFor |
genetic studies
drug testing lipid metabolism research |
| gptkbp:usedIn |
atherosclerosis research
|
| gptkbp:bfsParent |
gptkb:mouse_LDL_receptor
|
| gptkbp:bfsLayer |
7
|