Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
rare bleeding disorder
|
| gptkbp:affects |
blood coagulation
|
| gptkbp:alsoKnownAs |
hypoproconvertinemia
proconvertin deficiency |
| gptkbp:canBeCongenital |
yes
|
| gptkbp:causedBy |
mutation in F7 gene
|
| gptkbp:complication |
gastrointestinal bleeding
intracranial hemorrhage |
| gptkbp:diagnosedBy |
factor VII activity assay
prolonged prothrombin time (PT) |
| gptkbp:firstDescribed |
1951
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor VII deficiency
|
| gptkbp:ICD-10_code |
D68.1
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:MeSH_ID |
D005164
|
| gptkbp:obtainedFrom |
yes
|
| gptkbp:OMIM |
227500
|
| gptkbp:prevalence |
very rare
|
| gptkbp:symptom |
easy bruising
hemarthrosis menorrhagia nosebleeds prolonged bleeding after injury |
| gptkbp:treatment |
fresh frozen plasma
prothrombin complex concentrate recombinant activated factor VII |
| gptkbp:bfsParent |
gptkb:Factor_X_deficiency
|
| gptkbp:bfsLayer |
7
|