Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
peptide
opioid peptide |
| gptkbp:actsOn |
mu-opioid receptor agonist
|
| gptkbp:aminoAcidSequence |
H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
|
| gptkbp:CASNumber |
77780-75-5
|
| gptkbp:chemicalFormula |
C40H50N8O10
|
| gptkbp:compatibleWith |
human medical use
|
| gptkbp:discoveredBy |
gptkb:Erspamer_et_al.
|
| gptkbp:effect |
analgesic
potent opioid activity |
| gptkbp:firstDescribed |
1981
|
| gptkbp:firstIsolatedFrom |
gptkb:Phyllomedusa_sauvagei
|
| gptkbp:foundIn |
skin of Phyllomedusa frogs
|
| gptkbp:hasPotency |
30-40 times more potent than morphine (in some assays)
|
| gptkbp:hasUnusualResidue |
D-alanine at position 2
|
| gptkbp:heldBy |
heptapeptide
|
| https://www.w3.org/2000/01/rdf-schema#label |
dermorphin
|
| gptkbp:molecularWeight |
802.88 g/mol
|
| gptkbp:sideEffect |
respiratory depression
addiction potential |
| gptkbp:usedIn |
illicit performance enhancement in horse racing
|
| gptkbp:bfsParent |
gptkb:Phyllomedusa
|
| gptkbp:bfsLayer |
7
|