Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
disinfectant
|
| gptkbp:ATCCode |
D08AC02
|
| gptkbp:brand |
gptkb:Corsodyl
gptkb:Hibiclens gptkb:Peridex |
| gptkbp:CASNumber |
55-56-1
|
| gptkbp:chemicalFormula |
C22H30Cl2N10
|
| gptkbp:contraindication |
hypersensitivity to chlorhexidine
|
| gptkbp:discoveredBy |
gptkb:Imperial_Chemical_Industries
|
| gptkbp:discoveredIn |
1950s
|
| gptkbp:effect |
Gram-negative bacteria
Gram-positive bacteria |
| gptkbp:foundIn |
toothpaste
catheter coatings disinfectant solutions surgical scrubs wound cleansers |
| gptkbp:hasSaltForm |
chlorhexidine gluconate
chlorhexidine acetate chlorhexidine hydrochloride |
| https://www.w3.org/2000/01/rdf-schema#label |
chlorhexidine
|
| gptkbp:IUPACName |
1,1'-hexamethylenebis[5-(4-chlorophenyl)biguanide]
|
| gptkbp:legalStatus |
over-the-counter
|
| gptkbp:mechanismOfAction |
disrupts microbial cell membranes
|
| gptkbp:meltingPoint |
134°C
|
| gptkbp:molecularWeight |
505.45 g/mol
|
| gptkbp:notEffectiveAgainst |
bacterial spores
mycobacteria non-enveloped viruses |
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:PubChem_CID |
9552079
|
| gptkbp:riskFactor |
gptkb:contact_dermatitis
anaphylaxis (rare) |
| gptkbp:routeOfAdministration |
oral
topical intravenous catheter site |
| gptkbp:sideEffect |
allergic reaction
skin irritation taste alteration tooth staining |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:spectrumOfActivity |
broad-spectrum
|
| gptkbp:UNII |
O0G383GSIK
|
| gptkbp:usedFor |
wound cleaning
dental plaque control oral rinse preoperative skin preparation skin disinfection |
| gptkbp:WHOModelListOfEssentialMedicines |
true
|
| gptkbp:bfsParent |
gptkb:Mouthwash
|
| gptkbp:bfsLayer |
5
|