Statements (67)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:physicist
|
gptkbp:application |
gptkb:physicist
|
gptkbp:associated_with |
muscle development
muscle atrophy exercise-induced muscle damage muscle fiber repair muscle repair mechanisms |
gptkbp:clinical_trial |
diagnostic marker for LGMD
|
gptkbp:code |
calpain 3 protein
|
gptkbp:defense_mechanism |
muscle regeneration
|
gptkbp:discovered_by |
genetic research
|
gptkbp:formulation |
muscle differentiation
|
gptkbp:function |
calcium-dependent protease activity
|
gptkbp:future_plans |
targeted therapies
clinical interventions |
gptkbp:genetic_diversity |
gptkb:limb-girdle_muscular_dystrophy_type_2_A
|
gptkbp:has_impact_on |
muscle function
muscle hypertrophy |
gptkbp:has_method |
regulating cytoskeletal proteins
|
gptkbp:has_programs |
gene editing technologies
|
gptkbp:has_role |
cell signaling pathways
cellular signaling muscle repair |
gptkbp:has_variants |
single nucleotide polymorphisms
|
https://www.w3.org/2000/01/rdf-schema#label |
calpain 3 gene
|
gptkbp:influences |
muscle adaptation
muscle cell differentiation muscle cell survival muscle fiber type composition other muscle-related genes |
gptkbp:intelligence |
other species
|
gptkbp:is_associated_with |
reduced muscle strength
|
gptkbp:is_involved_in |
cell cycle regulation
cellular stress response calcium signaling protein degradation protein turnover |
gptkbp:is_known_for |
CAP N3
|
gptkbp:is_linked_to |
gptkb:Insurance_Company
metabolic disorders inflammatory responses muscle degeneration muscle fiber type transition muscle regeneration processes neuromuscular junction integrity |
gptkbp:is_noted_for |
diagnosis of myopathies
|
gptkbp:is_recognized_by |
1990s
gene sequencing |
gptkbp:is_represented_in |
skeletal muscle
|
gptkbp:is_studied_in |
animal models
therapeutic strategies exercise physiology therapeutic targets exercise recovery aging-related muscle loss |
gptkbp:located_in |
human chromosome 15
|
gptkbp:map |
genomic region 15q15.1
|
gptkbp:part_of |
calpain family
|
gptkbp:primary_function |
catalytic domain
|
gptkbp:regulates |
cellular apoptosis
|
gptkbp:regulatory_body |
gptkb:healthcare_organization
|
gptkbp:relationship |
other proteins
|
gptkbp:research_focus |
muscle diseases
|
gptkbp:research_interest |
biomarkers for muscle diseases
|
gptkbp:seed_dispersal |
protein-coding gene
|
gptkbp:social_responsibility |
gptkb:DJ
|
gptkbp:symptoms |
muscle weakness
|