|
gptkbp:instanceOf
|
gptkb:chemical_compound
antipsychotic medication
|
|
gptkbp:approvalYear
|
2008
|
|
gptkbp:approvedBy
|
gptkb:India
gptkb:Japan
gptkb:South_Korea
|
|
gptkbp:ATCCode
|
N05AE07
|
|
gptkbp:brand
|
Lonasen
|
|
gptkbp:CASNumber
|
132810-10-7
|
|
gptkbp:category
|
gptkb:piperazine
antipsychotic medication
sulfonamide
quinolone
fluoroarene
|
|
gptkbp:developedBy
|
gptkb:Dainippon_Sumitomo_Pharma
|
|
gptkbp:eliminationHalfLife
|
12 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasInChIKey
|
QZQZQKZQZQZQKZ-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C21H22FN3O4S
|
|
gptkbp:hasSMILES
|
CC1=CC2=C(C=C1)N=C(N2)N3CCN(CC3)C4=CC(=C(C=C4)F)S(=O)(=O)C5=CC=CC=C5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
blonanserin
|
|
gptkbp:KEGGID
|
D03273
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
dopamine D2 receptor antagonist
serotonin 5-HT2A receptor antagonist
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:molecularWeight
|
431.49 g/mol
|
|
gptkbp:pregnancyCategory
|
unknown
|
|
gptkbp:proteinBinding
|
high
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL2103837
184489
213021
DB12490
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
weight gain
insomnia
drowsiness
extrapyramidal symptoms
akathisia
elevated prolactin
|
|
gptkbp:UNII
|
2Z4K6X4IVL
|
|
gptkbp:usedFor
|
treatment of schizophrenia
treatment of delusional disorder
|
|
gptkbp:bfsParent
|
gptkb:D07481
gptkb:N05AX
|
|
gptkbp:bfsLayer
|
7
|