beta-(Aminomethyl)-4-chlorobenzenepropanoic acid

URI: https://gptkb.org/entity/beta-(Aminomethyl)-4-chlorobenzenepropanoic_acid
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:ATCCode M03BX01
gptkbp:bioavailability 70-80% (oral)
gptkbp:CASNumber 1134-47-0
gptkbp:drugClass muscle relaxant
gptkbp:eliminationHalfLife 2-6 hours
gptkbp:excretion renal
gptkbp:hasMolecularFormula C10H12ClNO2
gptkbp:hasSMILES C1=CC(=CC=C1C(CC(=O)O)CN)Cl
gptkbp:hasTherapeuticUse treatment of spasticity
gptkbp:hasUNII H789N3FKE8
https://www.w3.org/2000/01/rdf-schema#label beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
gptkbp:IUPACName 3-(4-chlorophenyl)-3-(aminomethyl)propanoic acid
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction GABA_B receptor agonist
gptkbp:meltingPoint 206-208 °C
gptkbp:metabolism minimal hepatic
gptkbp:otherName gptkb:Baclofen
gptkbp:pregnancyCategory C (US)
gptkbp:proteinBinding 30%
gptkbp:PubChem_CID gptkb:CHEMBL809
2284
2197
DB00181
gptkbp:routeOfAdministration oral
intrathecal
gptkbp:sideEffect dizziness
fatigue
drowsiness
weakness
gptkbp:bfsParent gptkb:baclofen
gptkbp:bfsLayer 7