autosomal dominant polycystic kidney disease
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:genetic_disorder
|
| gptkbp:abbreviation |
ADPKD
|
| gptkbp:affects |
gptkb:kidney
|
| gptkbp:complication |
chronic kidney disease
end-stage renal disease |
| gptkbp:diagnosedBy |
genetic testing
ultrasound |
| gptkbp:firstDescribed |
gptkb:Richard_Bright
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:MeSH_ID |
D007690
|
| gptkbp:mutationAssociatedWith |
PKD1 gene
PKD2 gene |
| gptkbp:OMIM |
173900
|
| gptkbp:prevalence |
1 in 400 to 1 in 1000 live births
|
| gptkbp:riskFactor |
cardiac valve abnormalities
colonic diverticula intracranial aneurysm liver cysts |
| gptkbp:symptom |
hypertension
hematuria flank pain renal cysts |
| gptkbp:treatment |
gptkb:dialysis
kidney transplantation blood pressure control tolvaptan |
| gptkbp:bfsParent |
gptkb:GANAB
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
autosomal dominant polycystic kidney disease
|