autosomal dominant polycystic kidney disease

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf genetic disorder
gptkbp:abbreviation ADPKD
gptkbp:affects gptkb:kidney
gptkbp:complication chronic kidney disease
end-stage renal disease
gptkbp:diagnosedBy genetic testing
ultrasound
gptkbp:firstDescribed gptkb:Richard_Bright
https://www.w3.org/2000/01/rdf-schema#label autosomal dominant polycystic kidney disease
gptkbp:inheritance autosomal dominant
gptkbp:MeSH_ID D007690
gptkbp:mutationAssociatedWith PKD1 gene
PKD2 gene
gptkbp:OMIM 173900
gptkbp:prevalence 1 in 400 to 1 in 1000 live births
gptkbp:riskFactor cardiac valve abnormalities
colonic diverticula
intracranial aneurysm
liver cysts
gptkbp:symptom hypertension
hematuria
flank pain
renal cysts
gptkbp:treatment dialysis
kidney transplantation
blood pressure control
tolvaptan
gptkbp:bfsParent gptkb:Samsca
gptkb:GANAB
gptkb:Jinarc
gptkb:Polycystic_kidney_disease
gptkbp:bfsLayer 7