| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:neurological_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:alsoKnownAs
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Kanner's_autism
                                        
                                         
                                    
                                        
                                            gptkb:classic_autism
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:characterizedBy
                                    
                                 | 
                                
                                    
                                        
                                            
                                            impaired communication
                                        
                                        
                                         
                                    
                                        
                                            
                                            impaired social interaction
                                        
                                        
                                         
                                    
                                        
                                            
                                            restricted and repetitive behavior
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:commonIn
                                    
                                 | 
                                
                                    
                                        
                                            
                                            males
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:diagnosedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:DSM-IV_criteria
                                        
                                         
                                    
                                        
                                            
                                            clinical assessment
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:differentialDiagnosis
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:intellectual_disability
                                        
                                         
                                    
                                        
                                            gptkb:Asperger_syndrome
                                        
                                         
                                    
                                        
                                            gptkb:Rett_syndrome
                                        
                                         
                                    
                                        
                                            gptkb:childhood_disintegrative_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:DSM-5_code
                                    
                                 | 
                                
                                    
                                        
                                            
                                            299.00
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:firstDescribed
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Leo_Kanner
                                        
                                         
                                    
                                        
                                            
                                            1943
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:ICD-10_code
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:F84.0
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:includedIn
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:pervasive_developmental_disorders
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:noKnownCure
                                    
                                 | 
                                
                                    
                                        
                                            
                                            true
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:notablePerson
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Temple_Grandin
                                        
                                         
                                    
                                        
                                            gptkb:Donna_Williams
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:onset
                                    
                                 | 
                                
                                    
                                        
                                            
                                            early childhood
                                        
                                        
                                         
                                    
                                        
                                            
                                            before age 3
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:partOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:autism_spectrum_disorder
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prevalence
                                    
                                 | 
                                
                                    
                                        
                                            
                                            less than 1% of population
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prognosis
                                    
                                 | 
                                
                                    
                                        
                                            
                                            lifelong condition
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:removes
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:DSM-5
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:replacedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:autism_spectrum_disorder_(DSM-5)
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:riskFactor
                                    
                                 | 
                                
                                    
                                        
                                            
                                            genetic factors
                                        
                                        
                                         
                                    
                                        
                                            
                                            advanced parental age
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:symptom
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:echolalia
                                        
                                         
                                    
                                        
                                            
                                            difficulty with social relationships
                                        
                                        
                                         
                                    
                                        
                                            
                                            insistence on sameness
                                        
                                        
                                         
                                    
                                        
                                            
                                            repetitive movements
                                        
                                        
                                         
                                    
                                        
                                            
                                            delayed speech development
                                        
                                        
                                         
                                    
                                        
                                            
                                            lack of eye contact
                                        
                                        
                                         
                                    
                                        
                                            
                                            difficulty adapting to change
                                        
                                        
                                         
                                    
                                        
                                            
                                            difficulty understanding nonverbal cues
                                        
                                        
                                         
                                    
                                        
                                            
                                            difficulty with imaginative play
                                        
                                        
                                         
                                    
                                        
                                            
                                            hyper- or hypo-reactivity to sensory input
                                        
                                        
                                         
                                    
                                        
                                            
                                            lack of interest in peers
                                        
                                        
                                         
                                    
                                        
                                            
                                            narrow, intense interests
                                        
                                        
                                         
                                    
                                        
                                            
                                            unusual sensory interests
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:treatment
                                    
                                 | 
                                
                                    
                                        
                                            
                                            behavioral therapy
                                        
                                        
                                         
                                    
                                        
                                            
                                            occupational therapy
                                        
                                        
                                         
                                    
                                        
                                            
                                            speech therapy
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:Autism_spectrum_disorder
                                        
                                         
                                    
                                        
                                            gptkb:autism_spectrum_conditions
                                        
                                         
                                    
                                        
                                            gptkb:autism_spectrum_disorder_(DSM-5)
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            7
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            autistic disorder
                                        
                                        
                                         
                                    
                                 |