Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
vaccine strain
|
| gptkbp:administeredBy |
injection
|
| gptkbp:component |
gptkb:TAK-003
CYD-TDV (Dengvaxia) TV003/TV005 |
| gptkbp:containsSerotype |
gptkb:DENV-1
gptkb:DENV-2 gptkb:DENV-3 gptkb:DENV-4 |
| gptkbp:contraindication |
pregnant women
immunocompromised individuals |
| gptkbp:developedBy |
biomedical researchers
|
| https://www.w3.org/2000/01/rdf-schema#label |
attenuated dengue virus
|
| gptkbp:inducedBy |
cell-mediated immunity
neutralizing antibodies |
| gptkbp:methodOfAttenuation |
genetic modification
serial passage in cell culture |
| gptkbp:purpose |
induce immunity against dengue virus
|
| gptkbp:reduces |
virulence
|
| gptkbp:regulates |
approved in some countries
under clinical trials |
| gptkbp:retains |
immunogenicity
|
| gptkbp:riskFactor |
mild dengue-like symptoms
rare severe adverse events |
| gptkbp:routeOfAdministration |
intramuscular
subcutaneous |
| gptkbp:storage |
refrigeration required
|
| gptkbp:target |
gptkb:dengue_hemorrhagic_fever
dengue fever |
| gptkbp:usedIn |
dengue vaccine
live attenuated tetravalent dengue vaccine |
| gptkbp:bfsParent |
gptkb:DENVax
|
| gptkbp:bfsLayer |
8
|