Properties (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
oligonucleotide
|
| gptkbp:canCreate |
nanoparticles
liposomes |
| gptkbp:designedFor |
bind complementary RNA
|
| gptkbp:developedBy |
therapeutic applications
|
| https://www.w3.org/2000/01/rdf-schema#label |
antisense oligonucleotides
|
| gptkbp:involvedIn |
RNA interference
|
| gptkbp:issuedBy |
injection
|
| gptkbp:isUsedFor |
clinical trials
genetic disorders personalized medicine improve patient outcomes cancer treatment study gene function viral infections diagnostic applications enhance therapeutic efficacy identify biomarkers develop new therapies reduce side effects improve delivery efficiency validate drug targets develop diagnostic tools modulate gene expression enhance vaccine efficacy aid in drug development alter splicing analyze RNA structure assess gene regulation create RNA-based therapeutics decrease toxicity enhance RNA stability evaluate therapeutic targets examine RNA stability facilitate functional genomics studies increase specificity inhibit translation investigate RNA localization investigate disease mechanisms modulate miRNA activity phosphorothioate chemistry promote RNA degradation reduce off-target effects reduce protein expression screen for drug candidates study RNA-protein interactions support gene therapy approaches suppress mutant alleles target disease-causing mutations target non-coding RNAs target specific isoforms track RNA dynamics |
| gptkbp:producedBy |
chemical methods
|
| gptkbp:targets |
gptkb:mRNA
|
| gptkbp:usedFor |
gene silencing
|