antibody-dependent enhancement (ADE)
GPTKB entity
Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological phenomenon
|
| gptkbp:associated_with |
secondary infections
live attenuated vaccines antibody titers |
| gptkbp:can_be |
vaccine trials
cross-reactive antibodies |
| gptkbp:causedBy |
increased disease severity
|
| gptkbp:diseaseResistance |
immune system function
|
| gptkbp:documentedIn |
clinical studies
|
| gptkbp:has_a_focus_on |
research funding agencies
|
| gptkbp:has_implications_for |
disease control strategies
|
| https://www.w3.org/2000/01/rdf-schema#label |
antibody-dependent enhancement (ADE)
|
| gptkbp:impact |
vaccine efficacy
|
| gptkbp:influence |
public health policies
|
| gptkbp:influenced |
antibody specificity
|
| gptkbp:involves |
antibodies
|
| gptkbp:is_a |
immunization programs
pandemic preparedness |
| gptkbp:is_a_document_that |
viral reactivation
|
| gptkbp:is_a_place_for |
vaccine design
|
| gptkbp:is_a_source_of |
pathogen entry
|
| gptkbp:is_a_subject_of |
epidemiological studies
scientific debate infectious disease specialists immunology research |
| gptkbp:is_a_way_to |
increased morbidity
viral persistence |
| gptkbp:is_characterized_by |
enhanced entry of virus into cells
|
| gptkbp:is_funded_by |
Fc receptors
|
| gptkbp:is_linked_to |
previous infections
antibody-dependent cellular phagocytosis |
| gptkbp:is_studied_in |
vaccine development
immune evasion |
| gptkbp:issues |
public health officials
COVID-19 vaccines infectious disease control vaccine manufacturers |
| gptkbp:leads |
immune response complications
|
| gptkbp:occursAnnually |
disease management strategies
viral outbreaks suboptimal neutralizing antibodies |
| gptkbp:performedBy |
multiple viral diseases
|
| gptkbp:related_to |
public health
therapeutic interventions |
| gptkbp:relatedTo |
viral infections
|
| gptkbp:resultedIn |
worsened clinical outcomes
|
| gptkbp:riskManagement |
severe disease outcomes
|
| gptkbp:visitedBy |
animal models
SARS-CoV-2 Zika virus dengue virus |
| gptkbp:was_a_factor_in |
clinical trial design
vaccine efficacy studies vaccine safety assessments vaccine_hesitancy vaccine_rollout_strategies |