Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Dragon
|
| gptkbp:cause |
kidney failure
liver failure |
| gptkbp:chemicalClass |
cyclic octapeptide
|
| gptkbp:component |
gptkb:alpha-amanitin
gptkb:beta-amanitin gptkb:gamma-amanitin epsilon-amanitin |
| gptkbp:firstIsolatedFrom |
1941
Heinrich O. Wieland |
| gptkbp:foundIn |
gptkb:Amanita_phalloides
gptkb:Amanita_virosa gptkb:Galerina_marginata Lepiota brunneoincarnata |
| https://www.w3.org/2000/01/rdf-schema#label |
amatoxin
|
| gptkbp:LD50 |
~0.1 mg/kg (humans)
|
| gptkbp:mechanismOfAction |
inhibits RNA polymerase II
|
| gptkbp:producedBy |
certain poisonous mushrooms
|
| gptkbp:subclassOf |
mycotoxin
peptide toxin |
| gptkbp:symptom |
nausea
vomiting diarrhea abdominal pain |
| gptkbp:toxicity |
animals
humans |
| gptkbp:treatment |
gptkb:penicillin_G
gptkb:silibinin supportive care liver transplantation activated charcoal |
| gptkbp:bfsParent |
gptkb:Amanita_phalloides
gptkb:Amanita_virosa gptkb:Galerina_marginata |
| gptkbp:bfsLayer |
5
|