Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
enzyme replacement therapy |
| gptkbp:administeredBy |
intravenous infusion
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA 2006 |
| gptkbp:ATCCode |
A16AB07
|
| gptkbp:brand |
gptkb:Myozyme
Lumizyme |
| gptkbp:CASNumber |
420784-05-0
|
| gptkbp:contraindication |
hypersensitivity to alglucosidase alfa
|
| gptkbp:cost |
high
|
| gptkbp:developedBy |
gptkb:Genzyme
|
| https://www.w3.org/2000/01/rdf-schema#label |
alglucosidase alfa
|
| gptkbp:indication |
gptkb:glycogen_storage_disease_type_II
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:macromoleculeType |
recombinant human protein
|
| gptkbp:mechanismOfAction |
replaces acid alpha-glucosidase
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
DB01272
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
anaphylaxis
infusion-related reactions |
| gptkbp:target |
lysosomal glycogen
|
| gptkbp:UNII |
6U8Z86QW8E
|
| gptkbp:usedFor |
gptkb:Pompe_disease
|
| gptkbp:bfsParent |
gptkb:Myozyme
|
| gptkbp:bfsLayer |
7
|